Topics related to the INTERVALS platform:
Beyond INTERVALS - tools, platforms, and resources of interest:
Share your data ↑
- How to prepare and upload data (html)
- How to prepare and upload data (pdf)
- How to format references?
- Summary dataset creation (pdf)
- Summary dataset metadata validation (pdf)
- Summary dataset tabular data validation (pdf)
- Summary dataset non-tabular data validation (pdf)
- Dummy example raw tabular dataset (pdf)
Editorial board ↑
Publication of scientific content on INTERVALS will be overseen by an Editorial Board (“EB”) consisting of experts in the areas of public health, toxicology, and systems biology, as well as statisticians, open science advocates, online database managers, and, of course, researchers studying the safety of consumer products, including tobacco and nicotine-containing products.
We are currently looking for editorial board members. More detail on the composition of the board and its function will be shared once the board is officially instated.
Where can I find a definition for terms used in this site?
You can find definitions of specific terms on the website Glossary
Who is developing and funding INTERVALS?
Philip Morris International R&D initiated the creation of INTERVALS with the intention to build an online platform enabling independent, third-party collaboration and data analysis by sharing protocols, tools, and data from assessment studies proactively. Data files are accompanied by the relevant information to foster reproducible research and by high-level summaries of obtained results. As the platform also hosts protocols and results from in vivo inhalation studies and in vitro studies describing the chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol from this and other candidate and potential modified risk tobacco products, it can serve as an invaluable source of scientific assessment data.
The site and associated data warehouse are developed in collaboration with Emakina and Edelweiss Connect GmbH.
What is the current scope of INTERVALS?
The INTERVALS platform and its associated data warehouse were created as a sharing platform for all studies, protocols, and data related to risk assessment of potential and candidate modified risk tobacco products as well as for reporting mechanistic investigations linked to tobacco-related diseases and pathways of toxicity.
How can I contribute?
Strengthened by community features, INTERVALS aims to enable the necessary dialogue between industry, independent reviewers, the public health community, the research community, and regulatory agencies that can validate the harm reduction potential of potential and candidate modified risk tobacco products.
Any institution producing relevant data on potential modified risk tobacco products (from aerosol characterization to molecular data) is invited to contribute to this infrastructure to facilitate scientific exchange and data reusability in the context of tobacco harm reduction.
The dedicated protocols page should also allow to share and improve methods used in 21st Century Toxicology as well as mechanistic investigation of key biological processes and diseases.